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鈥淲e were both surprised and disappointed to learn of Orelvis Martinez鈥檚 suspension,鈥� Jays general manager Ross Atkins said in a statement released Sunday morning. 鈥淲e will do everything in our power to ensure Orelvis has learned from this mistake.鈥�

Called up Tuesday to replace the injured Bo Bichette on the Jays鈥� active roster, Martinez made his first appearance on Friday night in Cleveland, playing second base and going 1-for-3 with a single in the Jays鈥� 7-1 loss.

Martinez hit 16 home runs in Triple-A Buffalo this season, leading the Jays organization and giving him 74 since the start of 2022.

The drug that turned up on the positive test was clomiphene, often used to treat infertility. When taken by women, it induces ovulation. When taken by men, it increases testosterone levels.

In a statement issued through the Major League Baseball Players鈥� Association, the 22-year-old explained that he and his girlfriend had been trying to start a family for the last couple of years and sought treatment privately.

Martinez added that his doctor 鈥渁ssured us this treatment (Rejun 50) did not include performance-enhancing drugs.鈥�

But it took less than a thirty-second Google search to discover Rejun 50 contains clomiphene, which is on Major League Baseball鈥檚 list of banned substances.

Chris Colabello is the only other active Jay to be suspended under MLB鈥檚 Joint Drug Prevention and Treatment Program. He was banned 80 games in April 2016.

Colabello had been a revelation with the American League East-winning 2015 club, batting .321 with 15 home runs and an .886 on-base-plus-slugging percentage 鈥� all career highs by a wide margin.

After receiving his ban for using chlorodehydromethyltestosterone, the then-32-year-old never played in the majors again.

The Blue Jays hope the outcome for Martinez will be different, but the list of players returning from a suspension for performance-enhancing drugs to have fruitful big-league careers is a short one.

San Diego鈥檚 Fernando Tatis Jr. was suspended 80 games in August of 2022 and came back to hit 25 home runs and win a gold glove last season. The 25-year-old went into Sunday鈥檚 games with an .821 OPS this season, still well above average but over 140 points below his pre-suspension average.

Tatis hit 42 home runs in 130 games in 2021. He has hit 39 home runs in 221 games since.

Jorge Polanco, then of the Minnesota Twins, was suspended 80 games going into the 2018 season and came back to have his only all-star appearance the next year. His .780 OPS post-suspension is better than the .739 he posted before, though 2017 was his first full season in the majors.

Pittsburgh鈥檚 Starling Marte got 80 games in the spring of 2017, coming off his first all-star season. He wasn鈥檛 an all-star again until 2022 as a member of the New York Mets, but there鈥檚 only an 11-point difference between his OPS pre- and post-suspension.

Six other position players have been suspended for using illegal performance-enhancing drugs since 2017 鈥� including Robinson Cano, who would have had a strong chance at being a Hall of Famer, twice 鈥� and none of them returned to being productive major-league hitters.

Martinez will be eligible to return on Sept. 22. The Jays鈥� final homestand of the year begins the next day.

The team went into Sunday鈥檚 game in Cleveland on a five-game losing streak, having fallen six games behind the Kansas City Royals for the final wild-card spot in the American League.

With a tough week ahead 鈥� three games in Boston and four at home against the first-place New York Yankees 鈥� the Jays could be on the verge of going into a youth movement for the second half of the season. Martinez could have been a central part of that.

He also could have been the most attractive piece the club could dangle in a trade if they decided to be buyers at the trade deadline. No one is going to be interested now.

Martinez will spend the rest of this season at the Jays鈥� player development complex in Dunedin, Fla., unable to participate in games.